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Purpose: To compare post?operative pain perception using bandage contact lens (BCL) stored at 2–8?C (Cold BCL, CL?BCL) or room temperature (23 – 25?C, RT?BCL) after photorefractive keratectomy (PRK) or corneal collagen?crosslinking (CXL) and determine status of nociception associated factors. Methods: In this prospective interventional study, 56 patients undergoing PRK for refractive correction and 100 keratoconus (KC) undergoing CXL were recruited following approval from the institutional ethics committee with informed consent. Patients undergoing bilateral PRK received RT?BCL on one eye and CL?BCL on the other. Pain was graded by Wong–Baker scoring on the first post?operative day (PoD1). Expression of transient receptor potential channels (TRPV1, TRPA1, TRPM8), calcitonin gene?related peptide (CGRP) and IL?6 was measured in cellular content from used BCLs collected on PoD1. Equal number of KC patients received RT?BCL or CL?BCL post?CXL. Pain was graded by Wong–Baker scoring on PoD1. Results: Pain scores on PoD1 were significantly (P < 0.0001) reduced in subjects receiving CL?BCL (Mean ± SD: 2.6 ± 2.1) compared to RT?BCL (6.0 ± 2.4) post?PRK. 80.4% of subjects reported reduced pain scores with CL?BCL. 19.6% reported no change or increased pain scores with CL?BCL. TRPM8 expression was significantly (P < 0.05) increased in BCL of subjects reporting reduced pain with CL?BCL compared to those who did not. Pain scores on PoD1 were significantly (P < 0.0001) reduced in subjects receiving CL?BCL (3.2 ± 2.1) compared to RT?BCL (7.2 ± 1.8) post?CXL. Conclusion: The simple approach of using a cold BCL post?operatively substantially reduced pain perception and could overcome post?operative pain?related limited acceptance of PRK/CXL.
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AIM:To assess the clinical efficacy of 5-fluorouracil(5-FU)and bandage contact lens in the pterygium excision combined with autogenous limbal stem cell transplantation(ALSCT)in treating patients with pterygium.METHODS:Random controlled clinical trial. A total of 71 patients(71 eyes)of pterygium who treated at the department of ophthalmology in Qinhuangdao Haigang Hospital between May 2021 and November 2022 were included. They were divide into three groups, including 23 eyes received pterygium excision combined with ALSCT in group A, 24 eyes that were administered with 5-FU intraoperatively and postoperatively in group B, and 24 eyes that received both bandage contact lens and 5-FU in group C. Furthermore, comfort levels at 1, 3, 7, 14d postoperatively, corneal epithelial healing at 1, 3, 7, 14d and 1mo postoperatively, treatment outcomes and complications at 3～6mo postoperatively were compared among the three groups of patients.RESULTS:The comfort levels at 1, 3 and 7d postoperatively and corneal healing at 1 and 3d postoperatively of the group C were better than those of the groups A and B. There were no statistical significant differences in the comfort levels at 14d after surgery and corneal healing at 14d and 1mo after surgery among the three groups of patients. Over a 3～6mo follow-up period, group A experienced recurrence in 3 eyes, group B had 1 recurrence, while group C had no recurrence. There were no statistically significant differences in complication rates among the three groups of patients.CONCLUSIONS: The application of 5-FU combined with bandage contact lens can enhance postoperative comfort levels, promote corneal epithelial healing, and improve the success rate in pterygium excision combined with ALSCT.
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@#AIM: To evaluate the efficacy evaluation of the combined application of bandage contact lens after pterygium excision surgery by Meta-analysis.<p>METHODS: Randomized controlled clinical studies on combined application of corneal bandage contact lens after pterygium excision were retrieved from PubMed, Cochrane Library, Wanfang, VIP, CNKI and other databases from May 2014 to May 2020. Data were extracted and Meta-analysis was performed.<p>RESULTS:Totally 11 randomized controlled clinical studies were included, including 10 in Chinese and 1 in English, with 864 patients. Meta-analysis results showed that 1d postoperative \〖<i>MD</i>= -1.57, 95%<i>CI</i>=(-1.72, -1.41), <i>P</i><0.00001\〗, 2d postoperative \〖<i>MD</i>= -1.35, 95%<i>CI</i>=(-1.59, -1.11), <i>P</i><0.00001\〗, 7d postoperative \〖<i>MD</i>= -0.64, 95%<i>CI</i>=(-0.78, -0.50), <i>P</i><0.00001\〗 combined application of corneal bandage contact lens can better reduce the degree of ocular pain in patients; And 1d postoperative \〖<i>MD</i>= -1.23, 95%<i>CI</i>=(-1.51, -0.95), <i>P</i><0.00001\〗, 7d postoperative\〖<i>MD</i>= -0.44, 95%<i>CI</i>=(-0.50, -0.39), <i>P</i><0.00001\〗 combined application of corneal bandage contact lens can better promote the condition of corneal epithelium. <p>CONCLUSION:The bandage contact lens could markedly release pain response after pterygium excision surgery, promote corneal epithelium recovery, which is beneficial to reduce the symptoms of clinical discomfort.
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@#AIM: To analyze the influence of bandage contact lens on corneal refractive status and postoperative complications in patients with pterygium. <p>METHODS: Totally 116 patients with pterygium treated in the hospital between January 2018 and December 2019 were recruited in the study. They were divided into control group and observation group by random number table method, 58 cases in each group. The control group received extended pterygium resection and autologous corneal limbal stem cell transplantation. On this basis, the observation group was treated with bandage contact lens. The best corrected visual acuity(BCVA), surface asymmetry index(SAI)of corneal topography, surface regularity index(SRI), corneal refractive power and postoperative complications in the two groups were compared. <p>RESULTS: Compared with preoperation, the BCVA of the two groups was significantly higher 1mo and 3mo after operation(<i>P</i><0.05), without statistically significant difference between the groups(<i>P</i>>0.05). Corneal horizontal and vertical curvature of the two groups were significantly higher, while corneal astigmatism was significantly lower at 1mo and 3mo after surgery. Meanwhile, the observation group had significantly lower corneal astigmatism than the control group(<i>P</i><0.05). SAI and SRI of the two groups significantly decreased, which were significantly lower in the observation group than in the control group(<i>P</i><0.05). No complications such as infection, poor healing of grafts and subconjunctival cysts were observed. The incidence of eye irritation was significantly lower in the observation group than in the control group, and lower at 2wk than at 1wk before operation(<i>P</i><0.05).<p>CONCLUSION: Extended pterygium resection combined with autologous corneal limbal stem cell transplantation and bandage contact lens is more conductive to the improvement of corneal refraction in patients with pterygium, which also can reduce the incidence of eye irritation.
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@#AIM: To evaluate the application value of 3g/L sodium hyaluronate eye drops combined with corneal bandage contact lens in the early stage of pterygium excision surgery.<p>METHODS: In this double blind randomized controlled study, 90 eyes of 90 patients with unilateral primary nasal pterygium who underwent surgical treatment from March 2017 to March 2018 were sorted into three groups, named as group A, group B and group C. Group A was treated with +3g/L sodium hyaluronate eye dropsand corneal bandage contact lens; group B was treated with +1g/L sodium hyaluronate eye drops and corneal bandage contact lens; and group C with +3g/L sodium hyaluronate and patching. Ocular surface irritation symptom scores, corneal epithelial healing time and conjunctival graft edema subsidence time of the three groups were compared after treatment.<p>RESULTS: Ocular surface irritation symptom scores in group A were lower than those in group C at all observation time points postoperatively(all <i>P</i><0.001); the corneal epithelial healing time(2.08±0.78d)and conjunctival graft edema subsidence time(4.62±1.17d)in group A were significantly shorter than those in group C with corneal epithelial healing time(5.13±2.34d)and conjunctival graft edema subsidence time(6.42±1.51d)(<i>P</i>=0.001, <i>P</i>=0.002). The corneal epithelial healing time was significantly shorterin group A when compared with group B(<i>P</i>=0.018), but there were no significant differences in ocular surface irritation symptom scores and conjunctival graft edema subsidence time between the two groups.<p>CONCLUSION: The combination of 3g/L sodium hyaluronate and corneal bandage contact lens has synergistic effect when applicated in the early stage after pterygium excision surgery, it can effectively shorten the corneal epithelial healing time as well as relieve irritation symptoms.
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@#AIM: To compare the measurement of intraocular pressure(IOP)through a bandage contact lens with the “native” measurement by rebound tonometry and non-contact tonometry in patients after pterygium excision. <p>METHODS: Fifty consecutive patients(50 eyes)undergone pterygium excision(unilateral nasal, primary pterygium, horizontal length <4mm), and conjunctival autografting were included in this prospective study. IOP measurements were obtained by Rebound tonometry and non-contact tonometry in random order with(lens measurement)and without(native measurement)a bandage contact lens half a month after operation. We compared the mean values(validity parameter)and standard deviation(precision parameter)of the two individual measurements in each case using the paired t-test 14d after surgery. <p>RESULTS: With the rebound tonometry we detected statistically significant higher values in the contact lens measurements(18.20±3.19 <i>vs</i> 15.17±3.80mmHg in the native measurements; <i>P</i><0.001), a good correlation with <i>r</i>=0.884 and mean difference was 3.04±1.79mmHg; With the non-contact tonometry we detected statistically significant higher values in the contact lens measurements(15.74±3.23 <i>vs</i> 13.19±3.89mmHg in the native measurements; <i>P</i><0.001), a good correlation with <i>r</i>=0.876 and mean difference was 2.55±1.88mmHg. In the contact lens measurements and native measurements, we detected statistically significant higher values by Rebound tonometry than that by non-contact tonometry(<i>P</i><0.001), and mean difference was 2.46±1.45mmHg, 1.98±1.67mmHg. <p>CONCLUSION: The use of rebound tonometry and non-contact tonometry shows good consistency between lens measurement and native measurement. However, it should be noted that the average of the measurements over contact lens by rebound tonometry and non-contact tonometry were found to be higher than that in native measurement, and the average of the measurements with and without lens by rebound tonometer was found to be higher than what was measured by non-contact tonometry.
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@#AIM: To compare the measurement of intraocular pressure(IOP)through a bandage contact lens with the “native” measurement by rebound tonometry and non-contact tonometry in patients after pterygium excision. <p>METHODS: Fifty consecutive patients(50 eyes)undergone pterygium excision(unilateral nasal, primary pterygium, horizontal length <4mm), and conjunctival autografting were included in this prospective study. IOP measurements were obtained by Rebound tonometry and non-contact tonometry in random order with(lens measurement)and without(native measurement)a bandage contact lens half a month after operation. We compared the mean values(validity parameter)and standard deviation(precision parameter)of the two individual measurements in each case using the paired t-test 14d after surgery. <p>RESULTS: With the rebound tonometry we detected statistically significant higher values in the contact lens measurements(18.20±3.19 <i>vs</i> 15.17±3.80mmHg in the native measurements; <i>P</i><0.001), a good correlation with <i>r</i>=0.884 and mean difference was 3.04±1.79mmHg; With the non-contact tonometry we detected statistically significant higher values in the contact lens measurements(15.74±3.23 <i>vs</i> 13.19±3.89mmHg in the native measurements; <i>P</i><0.001), a good correlation with <i>r</i>=0.876 and mean difference was 2.55±1.88mmHg. In the contact lens measurements and native measurements, we detected statistically significant higher values by Rebound tonometry than that by non-contact tonometry(<i>P</i><0.001), and mean difference was 2.46±1.45mmHg, 1.98±1.67mmHg. <p>CONCLUSION: The use of rebound tonometry and non-contact tonometry shows good consistency between lens measurement and native measurement. However, it should be noted that the average of the measurements over contact lens by rebound tonometry and non-contact tonometry were found to be higher than that in native measurement, and the average of the measurements with and without lens by rebound tonometer was found to be higher than what was measured by non-contact tonometry.
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Objective To evaluate the efficacy of corneal bandage contact lens or amniotic membrane in the treatment of pterygium.Methods A total of 114 patients (114 eyes) with primary pterygium treated in our hospital from April 2015 to December 2016 were randomly divided into amniotic membrane group (61 patients) and bandage contact lens group (53 patients).All patients underwent local anesthesia with pterygium excision combined with autologous free conjunctival flap transplantation by the same surgeon.In the amniotic membrane group,10 mm × 15 mm lyophilized biological amuiotic membrane was used,and its basal plane was applied to cover the keratoconjunctival wound of the patient,followed by fixation with a 10-0 nylon thread.In the bandage contact lens group,a piece of Bausch & Lomb pure vision chip was used to cover the patient's cornea.The best corrected visual acuity,surface asymmetry index (SAI),surface regularity index (SRI) and corneal astigmatism were recorded before and at 1 month and 3 months after operation.Wong-Baker face was used to score the pain intensity.Results Two weeks after operation,the fluorescein staining showed that positive staining presented in 7 eyes of the amniotic membrane group and in 1 eye of the bandage contact lens group,and the difference in the positive rate of both groups was statistically significant (P ＜ 0.05).There was no significant difference in the best corrected visual acuity between the two groups before and after the operation (all P ＞0.05).There was no significant difference in corneal astigmatism between the two groups before the surgery (P ＞ 0.05),but at 1 month and 3 months after operation,the bandage contact lens group was lower than the amniotic membrane group,and the differences were statistically significant (both P ＜ 0.05).The preoperative SRI and SAI of the amniotic membrane group were 1.52 ± 0.83 and 1.68 ± 0.62,respectively,as well as 1.61 ± 0.66 and 1.73 ± 0.59 in the bandage contact lens group,respectively,and there was no significant difference between the two groups (all P ＞ 0.05).At 1 month and 3 months after the treatment,the SRI (0.99 ±0.72,0.63 ±0.58) and SAI (0.61 ±0.53,0.54 ±0.28) in the bandage contact lens group were lower than those in the amniotic membrane group [(1.28 ± 0.67,0.85 ± 0.47) and (0.97 ± 0.47,0.82 ± 0.35)],and the differences were statistically significant (all P ＜ 0.05).On the day of the surgery and on the first day after surgery,the pain index of the bandage contact lens group was lower than that of the amuiotic membrane group,and the differences were statistically significant (all P ＜ 0.05).There was no significant difference in the pain index between the bandage contact lens group and the amniotic membrane group at 2 weeks postoperatively (P ＞ 0.05).Three months after operation,there was recurrence in one eye (1.64％) in the amniotic membrane group and two eyes (3.77％) in the bandage contact lens group,and the recurrence rate was not statistically different (P ＞ 0.05).Conclusion There are better improvment of corneal repair,lower corneal refraction and lower pain scores when the bandage contact lens is used in pterygium surgery when compared with amniotic membrane.
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· AIM:To investigate the effect of pterygium transplantation combined with amniotic membrane transplantation plus bandage type contact lenses.· METHODS:Totally 72 patients (80 eyes) with pterygium treated in our hospital from December 2014 to December 2016 were enrolled and divided into observation group and control group according to the randomized method,with 37 cases (41 eyes),35 cases (39 eyes) respectively.The control group was treated with pterygium transplantation combined with amniotic membrane transplantation.On the basis of this,the observation group received bandage contact lens.The postoperative visual acuity,curative effect,recurrence rate,and corneal healing time were recorded during the postoperative 1-year follow-up.Non contact tonometer was used to detect intraocular pressure (lOP) before operation and after operation 1d,1,3,6,and 12mo.Then the incidence of postoperative complications was recorded.· RESULTS:In order to determine the curative effect,a 4-grade standard was devised,from Ⅰ to Ⅳ.The postoperative efficacy of observation group consisted of 19 eyes in grade Ⅰ,11 eyes in grade Ⅱ,8 eyes in grade Ⅲ,3 eyes in grade Ⅳ,while the control group had 16 eyes in grade Ⅰ,12 eyes in grade Ⅱ,8 eyes in grade Ⅲ,3 eyes in grade Ⅳ,with no significant difference between two groups (P＞ 0.05).Visual acuity in the observation group increased in 20 eyes,remained in 17 eyes,and decreased in 4 eyes.In control group,visual acuity increased in 16 eyes,remained in 17 eyes,and decreased in 6 eyes,with no significant difference between two groups(P＞0.05).The corneal healing time was 3.43 ± 1.03d in the observation group and 5.13 ± 1.16d in the control group,which was significantly higher in the observation group than in the control group (P＜ 0.05).The lOP of the two groups before operation and after operation 1d,1,3,6,and 12mo showed no significant difference (P＞0.05).After the operation,only 1 eyes of corneal scar were found in the control group,and no other complications were found in the two groups such as intraocular pressure and corneal astigmatism.· CONCLUSION:Compared with pterygium transposition alone,combined amniotic membrane transplantation plus bandage contact lens is an effective and safe way to improve corneal healing time for patients with pterygium.
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AIM:To investigate the amniotic membrane transplantation for all the cornea or bandage contact lens after pterygium excision combine with limbal stem cell transplantation in the treatment of large pterygium.METHODS:The 40 eyes of larger pterygium was randomly divided into 2 groups,one group,20 eyes,with autologous limbal stem cell transplantation combine with amniotic membrane transplantation for all the cornea (amniotic membrane group);another group,20 eyes,with bandage contact lens after limbal stem cell transplantation (bandage contact lens group).The surgery time,eye comfort postoperation,progress in corneal healing were observed at 1,3d,1 and 3wk.RESULTS:The average surgery time of amniotic membrane transplantation group was 61.4±5.2min,and the bandage contact lens group was 34.5±2.7min,which was significantly shorter (Student's t-test,P＜ 0.05).There was no difference of the degree of eye comfort between the two groups at first day after surgery.But 3d and 1wk postoperation,the degree of ocular comfort of bandage contact lens group was much better than amniotic membrane transplantation group (P＜ 0.01),while there was no difference between the two groups 3wk after surgery (P＞0.05).The corneal healing score of the two groups was 0.85±0.18 and 1.15±0.18 in the 3wk after operation respectively,and the difference between the two groups was not statistically significant (Student's t-test,P=0.25).There was only one case of recurrence in amniotic membrane group.CONCLUSION:Treatment of larger pterygium with amniotic membrane transplantation for all the cornea or wearing bandage contact lenses after autologous limbal stem cell transplantation,can both ease eye symptoms and promote corneal wound healing.Those patients with bandage contact lens feel more comfortable and convenient than with autologous limbal stem cell transplantation.Also the bandage contact lens surgery is more economical than the other one.
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Objective To observe the effect of bandage contact lens on cornea epithelial healing after Epi-LASIK,and to evaluate the efficacy and safety.Methods Prospective case-control study.The 92 cases(181 eyes) performing Epi-LASIK were devided into observation group and control group.The 46 cases(91 eyes) of the control group were covered with routine nursing and the other 46 cases (90 eyes) of the observation group were served with bandage contact lens after Epi-LASIK.The symptoms and signs,time of corneal epithelial recovery,visual acuity and pain of postoperation of the two groups were examined within one week.Results After Epi-LASIK treatment,there was no significant difference in visual acuity between the two groups(P ＞ 0.05).At the 1 st,3rd,and 7th day after Epi-LASIK treatment,the ache grading results of the observation group were (2.53 ± 0.62),(1.39 ± 0.71),(0.07-± 0.25);and the ache grading results of control group were (3.22 ± 0.79),(1.74 ± 0.49),(0.26 ± 0.49).Pain scores of observation group were significantly lighter than that of the control group (P ＜ 0.05).After Epi-LASIK treatment,the average time of corneal wound healing in the observation group and control group were (2.80 ±0.86) days and (4.07 ±0.68) days respectively.The average time of postoperative corneal wound healing in the observation group was shorter than control group(P ＜ 0.05).Conclusion The application of bandage contact lens on cornea epithelial healing after Epi-LASIK treatment can reduce the pain of patients and promote the recovery of cornea in myopia patients.
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·AIM: To observe the effect of two kinds of bandage contact lenses on epithelial erosions and corneal thickness after vitreoretinal surgery for proliferative diabetic retinopathy ( PDR) .· METHODS: In this prospective, nonrandomized, comparative clinical study, 69 eyes of 69 patients with PDR were divided into two groups. They underwent vitreoretinal surgery. Group A, 36 eyes of 36 cases, the bandage contact lens with diameter of 13. 8mm were covered on corneal surface during surgery under noncontact wide-angle viewing systems. Group B, 33 eyes of 33 cases, the bandage contact lens with diameter of 14. 0mm were covered on corneal surface during the same surgery. Visual acuity, intraocular pressure, slit-lamp examination, corneal fluorescein sodium staining, count of corneal endothelium cells, measure of corneal thickness before and after operation were assessed.·RESULTS: Pre-operation, corneal fluorescein sodium staining positive rate was 42% in Group A and 42% in Group B (x2=0. 004, P=0. 949). At 1d after surgery, the positive rate of was 47% in Group A and 45% in Group B (x2=0. 022, P=0. 883). At 2d after surgery, the positive rate of was 44% in Group A and 45% in Group B ( x2 =0. 007, P=0. 933). At 3d after surgery, the positive rate of was 44% in Group A and 42% in Group B (x2=0. 029, P=0. 886). At 7d after surgery, the positive rate of was 42%in Group A and 39% in Group B (x2=0. 037, P=0. 848). Count of corneal endothelium cells showed no significant difference between Group A and Group B(P>0. 05). Count of corneal endothelium cells of Group A before surgery and at 7d after surgery were 2779. 25 ± 329. 55 /mm2 , 2777. 14±331. 17 /mm2, without significant difference (t=0. 551, P=0. 585);those of Group B were 2678. 61±335. 64/mm2 , 2672. 45 ± 336. 25 /mm2 , without significant difference(t = 1. 774, P = 0. 086). Measure of corneal thickness was 519. 25±23. 42μm before surgery and 542. 03± 25.94μm after surgery in Group A (t=-6.854, P<0.001). Measure of corneal thickness was 525. 64 ± 20. 97μm before surgery and 551. 33±27. 87μm after surgery in Group B (t=-7. 204, P<0. 001).·CONCLUSION:Two kinds of bandage contact lenses are used in vitreoretinal surgery in diabetic patients. The corneal epithelial integrity shows no difference before and after surgery. Both the bandage contact lens could protect the corneal epithelium and maintain good corneal transparency during vitreoretinal surgery.
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@#AIM: To evaluate the efficacy and characteristic of lock stitch suture with bandage contact lens for pterygium. <p>METHODS: A prospective randomized controlled double-blind study was conducted. Totally 140 cases(140 eyes)with pterygium were involved in the study from January 2014 to December 2015. All cases were randomly divided into two groups: 68 cases(68 eyes)in Group A received lock stitch suture, while 72 cases(72 eyes)in Group B received lock stitch suture with bandage contact lens. The postoperative reaction, effect, complications and so on were retrospectively analyzed between two groups. <p>RESULTS: One week later, the pain index scores at 1, 3 and 7d after surgery were 1.62±0.71, 0.83±0.52, 0.31±0.36 in Group A, and the pain index scores were 0.98±0.47,0.27±0.14, 0.12±0.21 in Group B, there were significant difference between the two groups(<i>t</i>=6.23, 8.56, 7.03, <i>P</i><0.05), and the difference were statistically significant within Group A and B(<i>F</i>=8.60, 13.60, <i>P</i><0.01); 4 of 68 eyes(5.9%)were recurrence after 1a in Group A and 4 of 72 eyes(5.6%)were recurrence in Group B, demonstrating no significant differences(<i>P</i>>0.05); 10 of 68 eyes(14.7%)with complications in Group A and 3 of 72 eyes(4.2%)with complications in Group B, demonstrating significant differences(<i>χ</i>2=4.61, <i>P</i><0.05). <p>CONCLUSION: A good result can be obtained by using the lock stitch suture with bandage contact lens in the treatment of pterygium. The lock stitch suture with bandage contact lens could significantly release pain response, it can significantly reduce the probability of the concurrent appearance.
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@#AIM: To investigate the effects of bandage contact lenses on corneal irritation and wound healing after deep corneal foreignbody removal.<p>METHODS: Forty-six patients(46 eyes)with deep corneal foreignbody removal were divided into two groups(23 patients for each). Both groups received deep corneal foreignbody removal. Patients of group 1 wore bandage contact lenses after the surgery,while patients of group 2 did not receive any further treatment after the surgery. The differences in eye irritation( at 1,3 and 7d)and corneal epithelial healing(at 7d)between the two groups were observed.<p>RESULTS: Mean pain scores were significantly lower in group 1(0.44±0.26, 0.26±0.14, 0.12±0.08)than in group 2(1.26±0.44, 1.02±0.38, 0.68±0.26)at 1, 3 and 7d after the surgery(<i>P</i><0.05). The rate of completely corneal epithelial healing at 7d were significantly higher in group 1(21 eyes, 91%)than in group 2(14 eyes,61%)(<i>P</i><0.05). <p>CONCLUSION: Bandage contact lenses will accelerate the recovery of corneal wounds,improve the healthcare efficiency and effectively alleviate eye irritation.
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AIM:To evaluate the application and effect of bandage contact lens in pterygium excision combined with conjunctival transplantation (CAT).METHODS:In a prospective, randomized, controlled clinical study, 110 patients (110 eyes) diagnosed with primary pterygium were collected in PLA NO.474 Hospital from January 2015 to January 2016.The 110 patients enrolled in the study in turn, and divided into two groups by the odd and even number.The odd number divided into bandage contact lens group (CAT + bandage contact lens, n=55), while the even number divided into control group (CAT, n=55).Visual analog scale (VAS) and corneal irritation were evaluated on 1, 3 and 7d after operation.Cornea fluorescent staining testing was carried out on 3d after operation.Following-up all the patients with 1a at least observed the recurrence of pterygium.RESULTS:The score of VAS in bandage contact lens group less than that in control group on 1d (4.13±2.06 vs 5.80±1.93, t=4.391, P<0.001) and 3d (2.09±1.36 vs 3.65±1.65, t=5.422, P<0.001) after operation, while there was no significant difference between two groups on 7d (t=1.295, P=0.198) after operation.The corneal irritation in bandage contact lens group less than that in control group on 1d and 3d after operation (P<0.05), while there was no significant difference between two groups on 7d after operation (P=0.052).Cornea fluorescent staining testing area in bandage contact lens group was less than that in control group on 7d after operation (0.33±0.37mm2 vs 2.73±2.21mm2, t=7.921, P<0.01).There was no significant difference in recurrence rate between two groups after 1a operation (P=1.000).CONCLUSION:Bandage contact lens could significantly release pain and corneal irritation, promote the healing of the corneal epitheliums in the defected area, and increase the postoperative comfort level in patients after operation.
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Objective To evaluate the clinical effect of bandage contact lens on patients after the pterygium excision surgery.Methods 200 patients with pterygium excision were used retrospectively analysis and were divided into control group and observation group by random digital table method.Patients in observation group wore bandage contact lens while those in control group did not (traditional method).The degree of pain in both groups was evaluated at 8 hours,24 hours and 48 hours after surgery.In addition,patients were surveyed for the satisfaction of our treatment when discharge.Results The ocular foreign body sensation,eye burning,tears and eye open difficult were obviously decreased in observation group (t=5.643,10.315,P ＜ 0.01).The overall comfort level of the patients in observation group was obviously improved.pain feeling of the eye after surgery in 8h,24h and 48h markedly decreased in observation group (t=6.196-12.495,P ＜ 0.01).The degree of satisfaction scores of preoperative guidancein,postoperative pain control,emotion,mental nursing,self-care ability,comfort in observation group were (1.59-0.62) points,(1.83±0.70) points,(1.42±0.68) points,(1.42±0.68) points,(1.48±0.67) points,(1.29±0.77) points,(1.43-0.64)points which were obviously increased than (0.76±0.55) points,(0.83±0.64points,(0.82±0.56) points,(0.80±0.47) points,(0.79±0.61) points,(0.66±0.54) points (t=4.311-9.354,all P＜ 0.01).Conclusions Compared with traditional treatment,bandage contact lens can significantly reduce the discomforts after the pterygium excision surgery,and increase the postoperative comforts of patients.It proves that bandage contact lens have extensive clinical value.
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AIM: To investigate the clinical safety and effectiveness of the two kind of bandage contact lenses: Senofilcon A (Johnson & Johnson Acuvue Oasys) and Balafilcon A ( Bausch& Lomb pure vision ) after laser - assisted subepithelial keratectomy (LASEK). METHODS: Thirty - eight patients (76 eyes) who had undergone the LASEK were divided into two groups. One group of patients wore Balafilcon A, the other group of patients fitted with Senofilcon A. The lenses were worn continuously for 7d. This was a seven - day experience and the patients scored for the symptom of the eyes (sore eyes, foreign body sensation and tearing) on the third day and the seventh day. Both of the two groups of patients taken off the soft contact lens on the seventh day and let their vision and corneal staining checked. RESULTS: The symptoms of eye sore and tearing of the two groups patients were different. The patients who wore the Senofilcon A were better. The pain of eyes were also different at 3 and 7d after surgeries(Z = - 4. 146, P =0. 000; Z= - 2. 814, P = 0. 005). The difference on tearing between the two groups at 3 and 7d after surgeries were significant ( Z = -2. 309, P = 0. 021; Z= -3. 276, P= 0. 001). There was no difference on sensation of dryness between the two groups at 3 and 7d after surgeries (Z= -0. 447, P=0. 655; Z= -0. 966, P = 0. 334). After the lenses were taken off, the visual acuity of patients wearing Senofilcon A was better ( t = 3. 800, P = 0. 001 ); corneal staining showed limited spots in 1- 2 quadrants with significant difference (Z= -2. 384,P= 0. 017). CONCLUSION: The Senofilcon A ( Johnson &Johnson Acuvue Oasys ) and Balafilcon A ( Bausch& Lomb pure vision) bandage contact lenses are safe and effective after LASEK, and the former is better than the latter in epithelial regeneration.
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PURPOSE: To evaluate the effect of rotary epithelial scrubber, cold BSS(R) irrigation, and bandage contact lens on the clinical outcome of excimer laser PRK. METHODS: This updated PRK was performed in 90 eyes (Group I: -4.54 +/- 0.91 D). Conventional PRK with mechanical epithelial removal using Beaver(R) blade and patch dressing was performed in 181 eyes (Group II: -4.30 +/- 0.97 D). Clinical outcome was compared between group I and group II retrospectively. RESULTS: Mean epithelial removal time was significantly shorter in group I (6.6 +/- 0.9 sec) than in group II (33.2 +/- 11.2 sec) (p<0.05). Mean epithelial healing time showed more rapid epithelial healing in group I (2.0 +/- 0.3 days) than in group II (3.0 +/- 1.0 days) (p<0.05). At 1 week and 24 months, UCVA of 0.7 or better was achieved in 91.1%, 97.8% in group I and in 71.8%, 88.2% in group II (p<0.05). At 6 and 24 months, spherical equivalent within 0.5 D of emmetropia was in 91.1%, 91.3% in group I and in 80.7%, 56.9% in group II (p<0.05). After 1 year follow-up, no eye in group I showed either corneal haze worse than grade 1 or loss of 2 or more lines of BSCVA. CONCLUSIONS: Updated PRK provided more rapid epithelialization than conventional PRK. And there was significant improvement in clinical outcome and safety in group I compared with group II. We suggested that updated PRK should be used for the correction of mild to moderate myopia.